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Description
Advanced Regenerative Therapy | Doctor-Led | Scalp Health Focus
Polynucleotides represent a next-generation regenerative treatment for hair and scalp health, designed to improve follicle function, scalp quality, and long-term hair growth at a cellular level.
At AesthetiCare Clinic in Moorgate, Central London, polynucleotide scalp treatments are offered as part of a doctor-led hair loss assessment, ensuring treatment is tailored to the underlying cause of hair thinning.
Unlike treatments that rely solely on growth factor stimulation, polynucleotides work by restoring the scalp environment itself. These injectable DNA-based molecules support cellular repair and regeneration, helping create the optimal conditions for natural hair growth.
By improving scalp health and reducing inflammation, polynucleotides help support the function of existing hair follicles and encourage stronger, healthier hair growth over time.
How Polynucleotides Work for Hair Loss
Polynucleotides are purified DNA fragments that help stimulate cellular repair and regeneration within the scalp.
When injected into targeted areas of the scalp, they support multiple biological processes involved in hair growth and follicle health.
Through a personalised, doctor-led approach, polynucleotides may help to:
• Encourage hair follicles to re-enter and remain in the active growth phase (anagen)
• Improve hair thickness, density, and overall hair quality
• Enhance scalp circulation, improving oxygen and nutrient delivery
• Stimulate fibroblast activity and collagen production, strengthening follicle support structures
• Reduce inflammation, helping create a calmer, healthier scalp environment
Because the treatment focuses on improving scalp health, it can be beneficial in patients where inflammation, hormonal factors, or environmental stressors contribute to hair thinning.
Who May Benefit from Polynucleotide Hair Treatments
Polynucleotide scalp treatments may be suitable for patients who:
• Are experiencing early or moderate hair thinning
• Have increased hair shedding
• Want to improve scalp health alongside hair growth
• Prefer a regenerative, non-hormonal treatment approach
• Are looking for an advanced alternative to traditional PRP treatments
As with all hair loss treatments, a consultation is essential to determine whether polynucleotides are likely to be effective for your specific hair loss pattern.
Treatment Course
Polynucleotides for hair restoration are typically performed as a course of treatments, as results develop gradually through sustained scalp regeneration.
Your treatment plan will be tailored to your:
• Hair loss pattern
• Scalp health
• Individual biological response
• Long-term hair goals
Course options and bundle pricing will be discussed during your consultation.
Treatment Details
Treatment time:
Approximately 20–30 minutes.
Downtime:
Minimal.
Common after-effects:
Mild scalp tenderness, sensitivity, or small injection marks may occur and typically settle within 24–48 hours.
Because hair growth cycles are slow, improvements in hair density or thickness usually develop gradually over several months.
Polynucleotides vs PRP for Hair Loss
Both PRP and polynucleotides are regenerative treatments used to support hair follicles and scalp health.
However, polynucleotides work differently from PRP by improving the overall scalp environment, rather than relying solely on platelet-derived growth factors.
Polynucleotides may offer advantages such as:
• More consistent biological response
• Reduced inflammation following treatment
• Improved scalp repair and regeneration
• Less reliance on individual platelet quality
In some patients, combining regenerative treatments such as PRP and polynucleotides may provide the most effective support for scalp health and follicular activity.
Treatment recommendations are always personalised following medical consultation.
Aftercare for Polynucleotide Scalp Treatment
Following treatment, mild scalp sensitivity may occur for a short period.
First 24 hours
• Avoid touching or massaging the scalp unnecessarily
• Avoid washing the hair
• Avoid strenuous exercise
First 48 hours
• Wash hair gently if needed
• Avoid excessive heat exposure such as saunas or steam rooms
• Avoid hair colouring or chemical treatments
General guidance
• Keep the scalp clean and well hydrated
• Maintain a balanced diet rich in essential nutrients for hair growth
If you have any concerns following treatment, please contact the clinic for advice.
Location
AesthetiCare Clinic is a doctor-led aesthetic and hair restoration clinic located in Moorgate, Central London, within the Integrity Centre at 87 Moorgate, EC2M 6SA.
The clinic is conveniently located for patients working in the City of London, including Bank, Liverpool Street, Barbican and Farringdon.
Frequently Asked Questions
What are polynucleotides for hair loss?
Polynucleotides are regenerative DNA-based molecules that help repair scalp tissue, reduce inflammation, and support healthier hair follicle function.
How many treatments are needed?
Most patients undergo a course of treatments, spaced several weeks apart, followed by maintenance sessions depending on individual response.
When will I see results?
Hair growth cycles are slow, so improvements in hair thickness or density usually develop gradually over several months.
Are polynucleotides better than PRP for hair loss?
Polynucleotides and PRP work differently. In many patients, polynucleotides may provide more consistent scalp regeneration, though treatment recommendations depend on the individual case.
